Abstract

Various preclinical studies have stated that members of the MYC transcription factor family (C-myc, L-myc and N-myc) are involved in disease progression and may represent promising therapeutic targets in small cell lung cancer (SCLC). However, there is limited knowledge on the clinical significance of MYC family members in surgically resected SCLC specimens. Our aim was to evaluate the expression and prognostic value of MYC family members in an international cohort of surgically resected SCLC patients.

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