Abstract

The recent successes of immunotherapy have shifted the paradigm in lung cancer treatment. Only a percentage of patients are responsive to immunotherapy, thus, it is imperative to identify factors impacting outcome. Body composition phenotypes may reflect aspects of patients’ immunology and thereby their ability to respond to immunotherapies. Therefore, our study aimed to describe the pre-treatment body composition profile of patients and explore the possible associations between these parameters and clinical outcomes in non-small-cell lung cancer (NSCLC) patients receiving first-line Pembrolizumab monotherapy.

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