EP1.16-10 Differentiation of Performance Status After Tumor Debulking in Malignant Central Airway Tumor via Rigid Bronchoscopy

Abstract

Bronchogenic carcinoma patients have been suffered from cancer and its complications. The aim of cancer treatment is for prolonged survival and symptomatic control. Novel multimodality treatment can be relieving symptoms and improve patients’ performance status (PS). Malignant central airway obstruction is the most harmful complication that increases morbidity, mortality and decreases PS. Rigid bronchoscopy with tumor resection plays pivotal roles for resolve these problems Retrospective Observational study enrolled cancer patients who had been suffered from malignant central airway obstruction that undergo Rigid bronchoscopy with tumor debulking in Phramongkutklao Hospital during January 2014 – October 2018 64 cancer patients were included in this study. 37(60.7%) were older than sixty. 36 (59%) were male and 38 (62.3%) had primary lung cancer in origin. 30 (49.2%) had left main bronchial obstruction 24(39.3%) had right main bronchial obstruction and 15(24.6%) had the tracheal obstruction. Most of patients 43(70.5%) had intraluminal obstruction and degree of obstruction were grade 4 39(63.9%). Pre-intervention ECOG 2-4 group were 23(37.7%), 24(39.3%) and 14(23%) respectively. Mean pre- intervention ECOG was 2.9±0.8 After rigid bronchoscopy with tumor debulking mean ECOG was decreased to 1.8 ±1.0. 46 of 64 (90.2%) had clinical improvement after successful procedure. 37 (72.5%) had 6-month survival and 33(64.7%) had 1-year survival after successful procedure, compared with 2(20%) and 1(10%) in unsuccessful procedure. 43(95.6%) had opportunity to received other treatment such as chemotherapy, targeted therapy, etc. after ECOG status was improveView Large Image Figure ViewerDownload Hi-res image Download (PPT) Rigid bronchoscopy with tumor debulking improves performance status, increases survival and increases opportunity for other new multimodality treatment in cancer patients who had malignant central airway obstruction.