Abstract
Approximately 50% of patients with lung adenocarcinoma (LUAD) in Asian populations harbor epidermal growth factor receptor (EGFR) mutations. Although the current front-line third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) targeted therapy can benefit these EGFR mutation-positive patients, treatments for non-small cell lung cancer (NSCLC) patients with EGFR-TKI resistance are limited. The study aimed to explore the application of both angiogenic and PD-1 blockade in NSCLC patients who had failed EGFR-TKIs.
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