Abstract

In advanced non-small cell lung cancer (aNSCLC), several clinical factors have been associated with prognosis in the context of the immunotherapy. Among them, female gender was proposed as negative factor for immuno-checkpoint inhibitors (ICI); however its independent impact of other prognostic factors (i.e., PS, smoking or biological parameters, etc) remains unclear. We assessed whether the female gender correlates with ICI-outcomes in patients with aNSCLC treated upfront with ICI-alone or combined to chemotherapy (CT).

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