Abstract

Despite the wide use of immunotherapy in the treatment of solid tumours, it is effective only in 20 - 40 % of patients according to histopathological type. The aim of our project is to predict response to immunotherapy based on a comprehensive analysis of the tumour, its microenvironment, and the host. To date, we have prospectively enrolled 70 patients with advanced or metastatic solid tumours who were treated with anti-PD-1 / anti-PDL-1 antibodies. Here we present preliminary results from a subanalysis of 23 patients with NSCLC.

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