Abstract

The patterns of failure (POF) of metastatic non-small cell lung cancer (mNSCLC) treated with first line pembrolizumab are not well described. If oligoprogression (OPD) occurs in a limited number of anatomic sites, local ablative therapy may allow continuation of otherwise effective immunotherapy (CPIs). We sought to characterize POF and OPD in this population and estimate the potential benefits of local therapy.

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