Year-end Sale % OFF 
Abstract
Pleural mesothelioma (PM) is a rapidly fatal tumor. The Cancer Genome Atlas (TCGA) investigation of PM revealed that patients with activated type-I interferon (IFN) pathway have a better clinical outcome. We recently demonstrated that the expression of endogenous retroviruses (ERV) due to promoter demethylation contributes to dsRNA formation and activation of type-I IFN signaling in an experimental mouse model of mesothelioma development. The aim of this study is to investigate ERV and type-I IFN activation in human PM.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
