EP02.45: Perinatal results in premature rupture of fetal membranes in pregnancies under 25 weeks: local experience – five years of follow‐up

Abstract

Determine obstetric and perinatal outcomes in pregnancies with premature rupture of membranes (PROM) before 25 weeks and their incidence according to gestational age at diagnosis at the Hospital Luis Tisné. A retrospective study was conducted of all pregnancies with a diagnosis of PROM occurring before 25 weeks and with a intrahospital management for more than 7 days between January 2013 and December 2017. 53 pregnancies were admitted, of which 36 pregnancies achieved 7 days of hospitalisation and these were analysed. 36 pregnancies were analysed with an average gestational age (EG) of 20 + 4 weeks (range 15 + 1 - 24 + 6 weeks), of which 23 (63%) had an RPM less than 22 weeks and 13 (37%) over 22 weeks, 29 (80%) were born alive. Of pregnancies less than 22 weeks, 10 (43%) newborns, were discharge, without major complications. On the other hand, of pregnancies greater than 22 weeks, 9 (69%) newborns are discharged. The most commonly reported maternal morbidity was miscarriage in 12 of the patients (40%). Regarding the delivery route of the survivors, 56.25% was a Caesarean delivery, and 43.75% vaginal delivery. Regarding comorbidities, it should be noted that of the pregnancies under 22 weeks, 100% had hyaline membrane disease, in less than 50%, the newborns presented pulmonary hypoplasia, bronchopulmonary dysplasia, intraventricular hemorrhage, necrotising enterocolitis, retinopathy of prematurity. Our results show that 32% of the patients admitted with a diagnosis of PROM present a fetal loss before the week. Of the patients who achieve a hospitalisation over 7 days, 80% (29 patients) of the pregnancies were born alive. Of these patients, 65.5% (19), survived at discharge. The group over 22 weeks shows the highest percentages of survival. However we have patients with PROM having less than 22 weeks were discharged without major complications. EP02.45: Table 1. Comorbidities Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.