Abstract

Stereotactic ablative body radiotherapy (SABR) is the standard of care for patients with early-stage lung cancer who are unable to undergo surgery. Although SABR is generally well-tolerated, radiation-induced lung injury (RILI) can occur in up to 58% of treated patients, which can be difficult to distinguish from local recurrence in follow-up imaging. Predictive markers that identify patients at greater risk of RILI may aid in the interpretation of post-treatment imaging. In this retrospective study, we investigated whether dosimetric data correlate with the relative volume of post-treatment RILI.

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