Abstract
Background All the current treatments of Parkinson’s disease can’t prevent the development of the disease. DBS is effective to improve the symptoms of Parkinson’s disease, but whether it can slow down the disease progression is still unclear. Casepresentation Here we report a case of a Parkinson’s disease with 27 years of disease course. He got the disease when he was 56 years old, and he could not walk in the 15th year after onset. After the DBS treatment, the patient’s symptoms improved, and he could look after himself in daily life. Because of scalp infection, in the 22nd year of the course of disease, DBS was taken out, but the symptoms of the patient are still better than those before DBS implanting for several years. He is alive till now. Conclusion This patient’s survival period is much longer than the general PD patients. DBS treatment may be the main reason for the delayed progression of disease and extended survival period. We speculate it may be associated with long-term DBS implantation which caused neural network remodeling and nerve protection.
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