Abstract
Absolute counts of the eosinophil cells of the blood and bone marrow were carried out in a haemocytometer and combined with autoradiographic studies of smears of blood and bone‐marrow suspensions from normal rats and cortisol‐treated rats. A certain parallelism was found between the number of circulating eosinophil leucocytes and the eosinophils of the bone marrow. Calculations showed that the bone marrow contains more than 50 times as many eosinophils as the blood. Single injections of Cortisol (5 mg intraperitoneally) as well as repeated injections of Cortisol (5 mg every 6 hours for up to 3 days) induced blood and bone‐marrow eosinopenia. The decrease in the number of eosinophils in the bone marrow appears to be due primarily to a decrease of mature (non‐prolifera ting) eosinophils. During repeated injections there was continued proliferation of eosinophil cells in the bone marrow, but mitotic activity was reduced. Appearances like those in the bone marrow have previously been observed in the spleen (Bro‐Rasmussen 1972 and 1973).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Acta pathologica et microbiologica Scandinavica. Section A, Pathology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
