Abstract
Two patients with eosinophilia, leukocytosis, hepatosplenomegaly, and thrombocytosis had decreased nuclear segmentation in their circulating eosinophils. This acquired Pelger-Huet anomaly was not seen in the polymorphonuclear neutrophils of these patients. Histochemical and electron microscopic examination of the morphologically abnormal cells confirmed their eosinophilic nature.
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