Abstract
Introduction: Osseous eosinophilic granulomas commonly occur in the skull, pelvis, vertebrae, mandible, and ribs. However, the eosinophilic granuloma in the sacrum is rare. Case presentation: We present the case of a 13-year-old Japanese boy, who presented with left low-back pain, and was diagnosed with eosinophilic granuloma arising in the sacrum. Computed tomography (CT) and magnetic resonance imaging demonstrated an osteolytic lesion with interruption of the cortex, and signal intensity changes at the left sacral body and wing. Histologic examination indicated an eosinophilic granuloma. Two years after CT-guided biopsy, the tumor had spontaneously healed completely, with no residual pain.Conclusion: The present case was eosiophilic granuloma arising from the rare site of sacrum. The tumor was completely remodeled two years after biopsy.
Highlights
Osseous eosinophilic granulomas commonly occur in the skull, pelvis, vertebrae, mandible, and ribs
Case presentation: We present the case of a 13-year-old Japanese boy, who presented with left low-back pain, and was diagnosed with eosinophilic granuloma arising in the sacrum
Computed tomography (CT) and magnetic resonance imaging demonstrated an osteolytic lesion with interruption of the cortex, and signal intensity changes at the left sacral body and wing
Summary
Eosinophilic granuloma is a benign tumor-like condition characterized by a clonal proliferation of Langerhans-type histiocytes in the bone or lung [1,2]. Eosinophilic granuloma of bone was initially described in 1940 [3,4], and its reported incidence is currently 0.05 - 0.5 per 100,000 children per year, with 90% of tumors occurring under the age of 15 years [5,6,7,8,9]. Regarding the location of osseous eosinophilic granulomas, the flat bones are involved in 70% of tumors, and the long bones in 30% [10]. To the best of our knowledge, only one report has previously described this type of tumor in the sacrum [11]. We describe here a case of eosinophilic granuloma of the sacrum, which spontaneously healed completely after biopsy
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