Eosinophilic esophagitis may persist after discontinuation of oral immunotherapy

Abstract

Eosinophilic esophagitis (EoE) is a chronic, inflammatory condition perpetuated by allergen exposure.1 Oral immunotherapy (OIT) is an emerging therapy for immunoglobulin (Ig) E–mediated food allergy that desensitizes patients to prevent harm from accidental exposure to a trigger food; however, EoE is a potential complication.2 The rate of OIT-induced EoE has been estimated at approximately 5%3; although most cases remit after stopping OIT.2