Eosinophilia in Children with Single and Mixed Soil Transmitted Helminthiasis

Abstract

Worldwide, helminthes infections are by far the leading cause of infection associated-eosinophilia and probably of eosinophilia of all causes. Due to behavioral aspects, partial immunity and other factors, prevalence rates and infection intensity are usually highest in children. Consequently, eosinophilia is common in tropical developing countries. Population based study in rural areas have demonstrated eosinophilia in up to 50 % in children and adults. The objective e of this study was to determine eosinophilia in children with Soil Transmitted Helminthiasis (STHs) of SD Panti Asuhan Al-Jamiyatul Washliyah Pulo Brayan Medan. This was an observational study with cross-sectional approach. In this study 82 children with STH enrolled. They are divided into two groups single and mixed STHs. All children were examined for eosinophilia. The results showed 40 children (48,8%) with single STHs; 42 children (51,2%) with mixed STH. Intensity of STHs were light infection 89%, moderate 7,3% and heavy infection 3,7%. Eosinophilia was found with mean 6,86% with SD 3,93 on single STHs and 10,12% with SD 6,34 on mixed STHs. It suggested that eosinophilia was higher on mixed STHs than single STH infection. Helminthic infection should be considered an importan cause of eosinophilia. The abscense of eosinophilia cannot exclude these parasites. However, the incidence and extent of infection related eosinophilia do not depend only on the type, intensity and stage of infection; other factors such as individual differences in innate and adaptive immune responses, epidemiological background, age at first exposure, underlying conditions, etc are important as well. There was a significant difference of eosinopnil value between single and mixed STHs on children of SD Panti Asuhan Al-Jamiyatul Washliyah Pulo Brayan Medan. Eosinophilia was higher in mixed STH Keywords : Eosinophil, eosinophilia, Soil Transmitted Helminthiasis, single and mixed STHs Biography : Panggabean Carolina Yoan Staff of Parasitology Department, Medical Faculty, University of Sumatera Utara Since joining the University of Sumatera Utara, Yoan Carolina Panggabean has been involved with studies related Parasitology. Since 2013 Yoan Carolina Panggabean worked as a lecture of Parasitology Department of Medical Faculty of University of Sumatera Utara. Contact Information : Medical Faculty University of Sumatera Utara Jl. Dr. Mansyur No. 5 Kampus USU Medan Telp. 081362419333 Email: carolina_yoan@yahoo.com