Abstract
(see 1 and 2). In addition, the method of study could be responsible for some of the variability of the eosinophil response. Before the direct chamber method of counting eosinophils was employed, sampling errors due to the small numbers of cells counted were so great that all but the most obvious changes in eosinophil counts were masked. The cause of eosinophilia when observed is not known. In the present study of patients and rats receiving fractionated partial-body treatments with X-rays and y-rays, the eosinophil response is analyzed in terms of certain biologic and physical factors. The effects of dose, portion of the body treated, sex, and species are considered. Also, the mechanisms that could be responsible for the eosinophilia observed in certain patients are discussed.
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