Abstract

Eosinophils are a type of leukocyte that have diverse functions in the body's response mechanisms to allergic reactions, cancer, parasitic infections, and fungal infections. Upon recruitment, eosinophils bind to pathogens and release antimicrobial cationic granule proteins. While also capable of engulfing pathogens, this phenomenon remains poorly characterized, particularly in comparison to that of their fellow granulocytes, neutrophils. Here we begin to address this gap by quantifying spreading events of eosinophils across IgG-opsonized surfaces in the presence and absence of serum.

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