Abstract
AbstractSignificant changes in the activities of the enzymes of methionine metabolism occur in the regenerating rat liver. We found that the levels of methionine adenosyl-transferase and cystathionine synthase increased immediately after partial hepatectomy. A secondary peak of activity was noted on the eighth postoperative day. In contrast, activities of both 5-methyltetrahydrofolate homocysteine methyltransferase and betaine-homocysteine methyltransferase declined. This pattern of changes suggests that transsulfuration, rather than methionine conservation, is a major metabolic response in hepatic regeneration.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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