Enzymes in Energy Metabolism, Introduction

Abstract

Several years ago, the bioenergetics subgroup decided to broaden the more narrow definition of bioenergetics to include all pathways involved in energy production. The importance of studying them in combination can be illustrated by the very different metabolic behavior of cancer cells that, in contrast to healthy cells, derive most of their energy from glycolysis and at the same time show a lack of apoptosis. While each presentation in this workshop will be focused on specific topics, glycolysis, the mitochondrial membrane system, the pyruvate dehydrogenase as part of the TCA cycle and the fumarate reductase as one of the enzymes in the mitochondrial respiratory chain, emphasis will be given to the interconnection between the different systems.