Abstract

Iron oxide nanoparticles perform biological activity under physiological conditions. They exhibit enzyme-like properties that catalyze redox reactions mediated by natural enzymes of oxidoreductase and are classified into a typical of nanozymes that are defined as nanomaterials with enzyme-like activities. In addition, iron oxide nanoparticles widely exist in biological system, such as magnetosome and ferritin that not only regulate iron metabolism, but also regulate ROS homostasis. The enzyme-like properties of iron oxide nanoparticles render them with broad biomedical applications including immunoassay, biosensor, antimicrobial, anti-tumor, antioxidant. Taken together, iron oxide nanoparticles are bioactive materials and may perform particular biological function in life activity.

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