Abstract

Marine invertebrates, such as oysters, mussels, clams, scallop, jellyfishes, squids, prawns, sea cucumbers and sea squirts, are consumed as foods. These edible marine invertebrates are sources of potent bioactive peptides. The last two decades have seen a surge of interest in the discovery of antioxidant peptides from edible marine invertebrates. Enzymatic hydrolysis is an efficient strategy commonly used for releasing antioxidant peptides from food proteins. A growing number of antioxidant peptide sequences have been identified from the enzymatic hydrolysates of edible marine invertebrates. Antioxidant peptides have potential applications in food, pharmaceuticals and cosmetics. In this review, we first give a brief overview of the current state of progress of antioxidant peptide research, with special attention to marine antioxidant peptides. We then focus on 22 investigations which identified 32 antioxidant peptides from enzymatic hydrolysates of edible marine invertebrates. Strategies adopted by various research groups in the purification and identification of the antioxidant peptides will be summarized. Structural characteristic of the peptide sequences in relation to their antioxidant activities will be reviewed. Potential applications of the peptide sequences and future research prospects will also be discussed.

Highlights

  • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are free radicals that play vital roles in the body, such as participating in intracellular signaling cascades and host defense against invading pathogens

  • We focus on antioxidant peptides purified and identified from enzymatic hydrolysates of edible marine invertebrates, including those prepared by using in vitro gastrointestinal digestion

  • Different types of chemical and cell-based assays have been used in the assay-guided purification and the characterization of antioxidant peptides from edible marine invertebrates (Table 2)

Read more

Summary

Introduction

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are free radicals that play vital roles in the body, such as participating in intracellular signaling cascades and host defense against invading pathogens. Imbalance between free radical production and endogenous antioxidant defense may result in cellular oxidative stress, causing oxidative damage to various cellular components, such as DNA, proteins and membrane lipids. Oxidative damage has been implicated in and is believed to be a key factor causing various pathological conditions, such as heart disease, stroke, arteriosclerosis, diabetes, and cancer [1,2,3,4]. Accumulation of oxidized proteins underlies the aging process in humans and the development of some age-related diseases [5]. The effectiveness of antioxidant therapies in preventing and/or managing human pathologies was highlighted [8,9,10]

Objectives
Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call