Enzyme‐Modified Hydrogel Coatings with Self‐Cleaning Abilities for Low Fouling PDMS Devices

Abstract

Enzyme-containing hydrogel coatings with abilities to automatically degrade proteins are developed by covalently binding proteases onto poly(ethylene glycol)/methacrylic acid hydrogel surfaces. Such active coatings can be easily applied to hydrophobic polydimethylsiloxane (PDMS) surfaces to impart long-term hydrophilicity and self-cleaning ability, providing an effective and environmentally friendly way to resist protein fouling in the biologically related application of PDMS-based devices. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.