Abstract
A comparison was made of enzyme levels for creatine phosphokinase (CPK), glutamic oxalacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), lactic dehydrogenase (LDH), and alpha hydroxybutyric dehydrogenase (HBD) in the serum and cerebrospinal fluid (CSF) of patients with eclampsia, pre-eclampsia, seizure disorders, and chronic hypertensive vascular disease. The eclamptic and, to a lesser extent, the pre-eclamptic patients had elevated serum GPT, GOT, HBD, and LDH that was attributed to segmental vasospasm, which is characteristic of both types of toxemias. Examination of the CSF revealed that eclamptic patients had elevated protein and enzyme levels which could be correlated to prognosis and diagnosis in the more severe cases. None of the other diseases studied caused an increase in these parameters of the CSF.
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