Abstract
Summary The activities of five enzymes involved in glucose utilization were measured in synchronized cultures of Chinese hamster cells. In the 12 h after mitosis, the activity per cell of glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, hexokinase, phosphoglucomutase, and glucose phosphate isomerase increased continuously to 180% of the initial values. The levels of oxidized and reduced pyridine nucleotides increased linearly, the ratio of oxidized-to-reduced forms remained constant, and the rates of oxygen consumption and lactate production were unchanged. These results suggest a stable basal cellular metabolism in these cells throughout interphase.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.