Abstract
Eighteen enzymatic loci were analysed in Aedes aegypti populations from four neighbourhoods in the city of Manaus. The analyses showed that the Downtown population was the most polymorphic (p = 55.6%) with higher observed and expected mean heterozygosities (Ho = 0.152 ± 0.052; He = 0.174 ± 0.052, respectively). The least variability was detected in the Coroado and Cidade Nova populations, both with polymorphism of 44.4%. The latter population presented the least observed heterozygosity (Ho = 0.109 ± 0.037). Wright's F statistics showed that the mean value of Fis was higher than that of Fst (Fis = 0.164 > Fst = 0.048), and from analysis of molecular variance (AMOVA) it was found that 95.12% of the variability is found within populations indicating a certain intra-population differentiation possibly of the microgeographic structure resulting from some barrier in the random coupling. Although the four populations were similar genetically (D = 0.003 to 0.016), the 4.88% differentiation was significant.
Highlights
Aedes (Stegomyia) aegypti is a widely geographically distributed species as well as of great epidemiological importance on account of being the major vector involved in the transmission of the yellow fever virus and four serotypes of dengue and its hemorrhagic fever viruses throughout most of the world’s tropical and subtropical areas (Chow et al, 1998).The reintroduction of this vector insect to Brazil in 1967, which is presently infesting up to 3,592 municipalities nationwide (Honório and Lourenço-de-Oliveira, 2001), has consolidated dengue infection as a major public health problem
Four populations of A. aegypti were analysed using enzymatic variation of 18 loci to characterize the genetic structure of this species in the sampled regions
The analysis of the polymorphism found in the four populations, through the allelic frequencies, showed that most loci in Hardy-Weinberg equilibrium were in the Compensa population
Summary
Aedes (Stegomyia) aegypti is a widely geographically distributed species as well as of great epidemiological importance on account of being the major vector involved in the transmission of the yellow fever virus and four serotypes of dengue and its hemorrhagic fever viruses throughout most of the world’s tropical and subtropical areas (Chow et al, 1998). The reintroduction of this vector insect to Brazil in 1967, which is presently infesting up to 3,592 municipalities nationwide (Honório and Lourenço-de-Oliveira, 2001), has consolidated dengue infection as a major public health problem. Four populations of A. aegypti were analysed using enzymatic variation of 18 loci to characterize the genetic structure of this species in the sampled regions
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