Abstract
Hydrolysis of 3,7-diacetoxycycloheptene using electric eel acetylcholinesterase gives optically pure (3R,7S)-3-hydroxy-7-acetoxycycloheptene, and hydrolysis using lipase enzyme from Candida cyclindracea gives the same hydroxy acetate, but in only 44% enantiomeric excess, in contrast to the normal behaviour of lipase which gives (S) alcohols for related hydrolyses; 3,7-diacetoxy-4,6-dimethylcycloheptene (10) is not hydrolysed by acetylcholinesterase, but is readily hydrolysed by lipase to give (3S,4R,6S,7R)-3-hydroxy-7-acetoxy-4,6-dimethylcycloheptene.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Chemical Communications
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
