Abstract
1,3-Butadiene is a major industrial chemical used in the production of synthetic elastomers such as polybutadiene and styrene-butadiene rubber (SBR). Like most of the unsaturated olefins, butadiene is metabolized in vivo. The first step of its biotransformation is the cytochrome P-450-dependent epoxidation to butadiene monoxide (Malvoisin et al, 1979). Both butadiene and butadiene monoxide have been shown to be mutagenic in the Ames test (de Meester et al, 1978).KeywordsStyrene OxideGlass Capillary ColumnCyclohexene OxidePeroxyacetic AcidVinyl CyclohexeneThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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