Abstract
The stereoselective acylation of meso-5-bis(hydroxymethyl)tetrahydro-2-funanone 1 by vinyl acetate or vinyl myristoate in the presence of Pseudomonas cepacia lipase in organic media gave the corresponding ( S)-monoesters in high enantiomeric excess. The hydrolysis of the corresponding diacetate in the presence of the same enzyme provided the ( R)-monoacetate.
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