Abstract
The influence of anabolic steroid nandrolone and antibacterial agent sulfa-nilamide on the enzymatic activity in the gills of the two-year-old carps was investigated. Different concentrations of nandrolone and sulfanilamide in water over 72 h did not affect the morphological indices of the internal organs, the external body covers and behavior of the two-year-old carps, but alter the enzymatic activity in their gills. Sulfanilamide of concentrations 1.10 and 6.30 mg/dm3 over 72 h reduced the alkaline phosphatase activity by 26.7% as compared with control, but did not affect the alanine and aspartate aminotransferase activity. Under nandrolone concentration 0.1 mg/dm3 the alkaline phosphatase activity in gills decreased by 15.4%, and under 1.0 mg/dm3 - by 23.0% as compared with control, the alanine and aspartate aminotransferase activity was not changed. The obtained results indicate the importance of alkaline phosphatase in fish gills for evaluation of the xenobiotics sulfanilamide and nandrolone effects on the organism of the freshwater fishes.
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