Environmental rotenone treatment destroys primary receptor neurons in the pond Snaillymnaea Stagnalis

Abstract

Event Abstract Back to Event Environmental rotenone treatment destroys primary receptor neurons in the pond Snaillymnaea Stagnalis Agnes Vehovszky1*, H. Szabo1 and L. Hernadi1 1 Balaton Limnological Research Institute, HAS, Hungary Environmental rotenon treatment of Lymnaea stagnalis attenuates the DAergic functions, resulting locomotory impairment and decreased feeding behavior in a concentration dependent manner. However, we do not know if the attenuated central DAergic system is responsible for the decreased behavioral responses or rotenone primarily destroys the sensory neurons in the skin or the buccal areas which may lead to the cessation of behaviors. Morphological strudies were carried out to test the effects of environmental rotenon treatment (0.5 uM) on primary sensory neurons located in the oral-buccal areas to determine whether impairment of the sensory system leads to the decreased feeding behavior of treated animals. Retrograde neurobiotin tracing via cerebral and buccal nerves which innervate head areas and the oral-buccal cavity revealed a huge number of primary sensory neurons labeled in the lips, and the oral cavity. The tracing via buccal nerves revealed a huge number of labeled sensory neurons in the bucal cavity and the ventral part of the oral cavity which is also innervated by a cerebral nerve. Tracing via cerebro-buccal connectives revealed that a low number of sensory neurons are labeled in the lips and the oral cavity. In rotenon treated animals the neurobiotin tracing via cerebral and buccal nerves failed to label primary sensory neurons either in the lips and mouth or the oral-buccal cavity suggesting that rotenon treatment destroyed primary sensory neurons in body surfaces exposed to rotenone. Since the activity of these sensory cells is required to the initiation of feeding CPG therefore their degeneration may be responsible for the cessation of Lymnaea food intake. Conference: 12th Meeting of the Hungarian Neuroscience Society, Budapest, Hungary, 22 Jan - 24 Jan, 2009. Presentation Type: Poster Presentation Topic: Pathophysiology and neurology - degenerative disorders Citation: Vehovszky A, Szabo H and Hernadi L (2009). Environmental rotenone treatment destroys primary receptor neurons in the pond Snaillymnaea Stagnalis. Front. Syst. Neurosci. Conference Abstract: 12th Meeting of the Hungarian Neuroscience Society. doi: 10.3389/conf.neuro.01.2009.04.179 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 05 Mar 2009; Published Online: 05 Mar 2009. * Correspondence: Agnes Vehovszky, Balaton Limnological Research Institute, HAS, Tihany, Hungary, agnes@tres.blki.hu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Agnes Vehovszky H. Szabo L. Hernadi Google Agnes Vehovszky H. Szabo L. Hernadi Google Scholar Agnes Vehovszky H. Szabo L. Hernadi PubMed Agnes Vehovszky H. Szabo L. Hernadi Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.