Abstract
S15: Interaction between environmental chemicals and toxicants and the human microbiome, Room 217, Floor 2, August 28, 2019, 10:30 AM - 12:00 PM The influence of the microbiome on human health is a rapidly emerging area of investigation. This talk will cover both epidemiology and experimental study to highlight the latest evidence regarding how inhaled exposures affect human airways. The evidence will be divided into three sections, addressing: a) How inhalants may change the airway microbiome, directly or indirectly, by: i) acting as vectors for microbiome; ii) changing preexisting airway microbiome, whether by changing immunity or through other mechanisms b) How existing airway microbiome modifies response to environment c) How inhalants may affect the airways through the gut-lung axis Key inhalants of concern will include traffic-related air pollution, cigarette smoke and e-cigarette vapour. Future research directions, including potential for intervention and remediation, will be discussed.
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