Enumeration of cytomegalovirus-specific interferon CD8+ and CD4+ T cells early after allogeneic stem cell transplantation may identify patients at risk of active cytomegalovirus infection

Abstract

Recovery of functional cytomegalovirus (CMV)-specific T lymphocytes is critical for protection from active CMV infection and disease in allogeneic stem cell transplant recipients (Allo-SCT).[1][1]–[6][2] To date, assessment of CMV-specific T-cell immunity has not had a major impact on the clinical