Entropy of motor unit activity and surface electromyogram in an isometric force task

Abstract

Neuromuscular function is typically evaluated by recording the surface electromyogram (sEMG) in different motor tasks. Linear stochastic signal analysis is largely employed to extract information from sEMG and motor unit activities, even though there are well known nonlinearities in the neuromuscular system. Measures based on information theory have been used in the neuroscience. These measures are model-independent that can capture both linear and nonlinear features of time series. Here, we used Shannon’s entropy to quantify the neural information present in (1) the single motor unit spike trains, (2) compound spike trains (a population signal), and (3) sEMG envelope (a gross measure of muscle electrical activity). Participants performed isometric force control tasks in two contraction intensities (2.5% and 5% of maximum voluntary contraction). We also calculated the correlation (linear regression model) between the entropy and either the coefficient of variation of muscle force or mean motor unit firing rate. Results showed that entropy increases with force level and it is higher for the spike trains. In addition, spike train entropy has moderate correlation with the mean motor unit firing rate. The results are quite promising, and they show that measures from information theory can be applied to signals from motor unit activities to differentiate contraction intensities and, with further analysis, to understand the nonlinear properties of the neuromuscular system.