Abstract
The entire nucleotide sequence of mitochondrial DNA of MS/Ae mice was determined. It consists of 16,300 bases, with 15 sites being different from the known 16,295 base sequence of mitochondrial DNA derived from L cells of C3H mice (accession no. V00711). The MS/Ae strain is a derivative of CD-1 mice; these 15 sites in mitochondrial DNA from CD-1 mice were also determined. No difference was found, strongly suggesting that mitochondria of MS/Ae and CD-1 mice have the same DNA sequence and indicating that the high sensitivity of MS/Ae mice to mutagens compared to CD-1 mice is not dependent on genes coded by mitochondrial DNA. (The nucleotide sequence data in this article will appear in the DDBJ, EMBL, and GenBank nucleotide sequence database with the following accession number: D83491).
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