Enthalpies of mixing ofR- andS- enantiomers of propane-1,2-diol and methyllactate at 298.15 K

Abstract

Enthalpies of mixing of chiral isomers R- and S- of propane-1,2-diol and methyllactate, respectively, have been measured over the whole range of mole fraction at 298.15 K. All the enthalpies of mixing measured are very small. The enthalpic differences between the interactions of molecules of like-configuration and those of opposite configuration have been evaluated precisely. Mixing of R- and S-enantiomers of propane-1,2-diol gives slight enthalpic stabilisation over the whole range of mole fraction, however methyllactate has shown the opposite effect on mixing. Chirality 10:722–725, 1998. © 1998 Wiley-Liss, Inc.