Abstract
Enteroviruses are prevalent globally. They are transmitted by the fecal oral route and also the respiratory route. Although these viruses cause mild febrile symptoms in immunocompetent humans, their infections result in a wide range of diseases in the neonates and young infants. The pathogenesis of these viruses depends on the host and virus factors. This mini-review makes the readers aware of the seriousness of enterovirus infections in the pediatric population, and to show the necessity of the molecular diagnostics.
Highlights
Enterovirus (EV) infections are common, and their frequent mode of transmission is by the fecal-oral and respiratory routes
Typical symptoms associated with enterovirus infections of immunocompetent population are mild fever, febrile conditions, and in specific cases they are associated with severe clinical manifestations such as meningitis, encephalitis, and myocarditis
These viruses are associated with chronic infections associated with autoimmunity such as type 1 diabetes (T1D), dilated cardiomyopathy (DCM) [2,3,4]
Summary
They are transmitted by the fecal oral route and the respiratory route These viruses cause mild febrile symptoms in immunocompetent humans, their infections result in a wide range of diseases in the neonates and young infants. Typical symptoms associated with enterovirus infections of immunocompetent population are mild fever, febrile conditions, and in specific cases they are associated with severe clinical manifestations such as meningitis, encephalitis, and myocarditis. These viruses are associated with chronic infections associated with autoimmunity such as type 1 diabetes (T1D), dilated cardiomyopathy (DCM) [2,3,4]. Enteroviruses are ubiquitous, the several species, genotypes and multitropism causing varying clinical manisfestations makes their diagnosis challenging and yet necessary
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