Enterocutaneous fistula: Successful treatment of two cases with urinary bladder matrix xenograft

Abstract

Introduction: Enterocutaneous fistula (EcF) represents a challenging clinical condition in surgery. two cases of EcF are presented that were successfully treated with Matristem, a porcine urinary bladder matrix xenograft application. case series: the cases were treated with a procedure involving curettage of the tract, followed by injection of a Matristem slurry, and insertion of a rolled Matristem graft. In both cases, the EcF ceased to drain bilious fluid. After a week, both patients began a liquid diet, and no recurrent fistula occurred after six months of follow-up. conclusion: In this study, treatment of EcF using Matristem resulted in successful clinical healing of the EcF. the use of biologically derived materials for EcF is a relatively new concept. there is precedent for using biological plugs with some reported examples of success, but use of porcine urinary bladder matrix is novel for this purpose.