ENTERIC INSUFFICIENCY SYNDROME IN SURGICAL PATIENTS: OBJECTIVE REALITY OR A SYMPTOM OF THE DISEASE?

Abstract

Acute surgical diseases and trauma in some cases are accompanied by the development of enteric insu ffi ciency syndrome, which aggravates the course of the underlying disease and increases mortality.The purpose of this scientifi c review is to focus the attention of clinicians on the emergence of enteric insu ffi ciency syndrome in the course of acute surgical pathology and traumatic disease, which requires the use of individualized treatment measures.Results. In acute surgical pathology and traumatic disease, a complex structural and functional reorganization of the intestinal epithelium occurs, which disrupts the interrelationships between the cells of the intestinal epithelium, the rejection of epithelial cells and, as a result, the penetration of bacteria from the lumen of the intestine into the lamina propria, their accumulation in the stroma of microvilli and translocation into the free peritoneal cavity. Morphologically it manifests itself in the form of erosion and ulcerative defect or phlegmonous enteritis. As a result, an endotoxemia syndrome is formed, which is the cause of the development of multiple organ failure in such patients Conclusion. The syndrome of enteric insu ffi ciency in acute surgical pathology of the organs of the peritoneal cavity and injuries is a clinically, laboratory and morphologically proven condition that has periods of progress and corresponding clinical symptoms.