Abstract
Enteric Coronavirus in Ferrets, the Netherlands
Highlights
To the Editor: Coronaviruses (CoVs) are enveloped, positive-sense, single-stranded RNA viruses that can cause acute and chronic respiratory, enteric, and central nervous system disease in a variety of animal species [1]
A novel ferret enteric CoV (FRECV) was indentified in domesticated ferrets (Mustela putorius) in which epizootic catarrhal enteritis had been diagnosed; the illness was characterized by foulsmelling green diarrhea with high mucus content, lethargy, anorexia, and vomiting [2]
To test for a CoV in these animals, we analyzed RNA extracted from rectal swabs with a degenerate set of primers to amplify a conserved region within open reading frame (ORF) 1 of CoVs [7]
Summary
To the Editor: Coronaviruses (CoVs) are enveloped, positive-sense, single-stranded RNA viruses that can cause acute and chronic respiratory, enteric, and central nervous system disease in a variety of animal species [1]. Amino acid alignment of 1 of these sequences (FRCoV-511c) with FRECV-MSU2 demonstrated 91.8% identity and 95.7% similarity, whereas this virus shows 89.3% identity and 95.2% similarity to ferret systemic CoV (FRSCV-MSU1).
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