Enteral Nutrition Intervention Enhances Analgesic Effect of Morphine Hydrochloride Sustained Release Tablets in Alleviating Cancer Pain

Abstract

We have explored the effects of enteral nutrition interventions on the analgesic effect of morphine hydrochloride sustained-release tablets in cancer pain therapy. Patients in the control group were monitored in real time, and analgesics were given as needed to improve the pain. Patients in the treatment group received both morphine hydrochloride sustained-release tablets and enteral nutrition interventions. After treatment, the Visual Analogue Scale score, unified Parkinson’s disease rating scale, and Pittsburgh sleep quality index scores in the treatment group were reduced relative to the control group, and Parkinson’s disease sleep scale scores and nutritional indexes were elevated. Levels of interferon-γ and interleukin-2 in the treatment group were elevated relative to the control group, while the levels of interleukin-4 were reduced. The incidence of adverse reactions in the treatment group was 15.79% (21/133), which was lower relative to the control group (31.58%, 42/133). Levels of 5-hydroxytryptamine and brain-derived neurotrophic factor in the treatment group were elevated relative to the control group, while the levels of dopamine declined. To sum up, morphine hydrochloride sustained-release tablets combined with enteral nutrition interventions can decrease the inflammatory response of patients and promote sleep quality