Abstract

Introduction: Tenofovir disoproxil fumarate (TDF) is a recommended first-line therapy for chronic hepatitis B (CHB) patients. However, reduced estimated glomerular filtration rate (eGFR), hypophosphatemia and Fanconi syndrome have been reported in some TDF-treated patients. We assessed whether entecavir (ETV) may be a safe and effective rescue strategy for such patients.

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