Abstract

STUDIES ON THE BIOLOGY OF THE PERIODONTIUM OF MARMOSETS: IX. EFFECT OF PARATHYROID HORMONE ON THE ALVEOLAR BONE OF MARMOSETS PRETREATED WITH FLUORIDATED AND NONFLUORIDATED DRINKING WATER Levy, B. M . , Dreizen, S.,Bernick, S., and Hampton, J. K., Jr. J. Dent. Res., 49:816, 1970 Forty-four young adult marmosets were divided into two groups of 20 and 24 animals each. The two groups were fed normal diets with the latter receiving drinking water containing 50 ppm fluoride. After five months twelve and ten animals from the above groups respectively were given parathyroid hormone in divided doses. The remaining marmosets served as controls and all animals were sacrificed following administration of the parathyroid hormone. The skulls were fixed and studied histologically. The results showed that pretreatment of animals with fluoridated drinking water gave minimal histologic evidence of alveolar bone resorption when injected with 300 to 600 U S P units of parathyroid hormone. Fluoride pretreated animals injected with 800 U S P units of parathyroid hormone showed a partial suppression of alveolar bone loss over the control group. University of Texas Dental Science Institute at Houston, Houston, Texas 77025. QUANTITATIVE PARAMETERS OF EARLY HUMAN GINGIVAL INFLAMMATION Schroeder, H. E . Arch. Oral Biol. 15:383, 1970 Ten biopsies were taken from human gingiva six to 24 months after eruption of premolar teeth indicated for extraction for orthodontic purposes. All teeth had a PMA of zero or one. Microscopic examination of prepared specimens revealed no evidence morphologically of reduced ameloblasts present after one year. The volume of leukocytes was greater cervically than apically with the maximum at the bottom of the sulcus. The thickness of the attached epithelium was also greater coronally than apically. Polymorphonuclear leukocytes were the prevailing cells in the epithelium and they transmigrated the epithelial attachment. Plasma cells were the prevailing cells in the connective tissue. The distribution of leukocytes was not correlated with the area or thickness of the epithelial attachment. The degree of inflammation observed clinically appeared to be the result of only one measurement, that is, the extension of inflammation into the connective tissue. Laboratory of Electron Microscopy, Department of Operative Dentistry and Periodontology, Dental Institute, University of Zurich, Zurich, Switzerland.

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