Abstract
The rapid adaptability of bacteria to antibiotic-based therapy makes the development of effective medicines for infectious illnesses a complex and continuous process. Nevertheless, well-thought-out activity enhancers, such as antibiotic delivery systems, can boost the efficacy of the drugs now in use, defeating antimicrobial resistance and lowering the likelihood of fostering more bacterial resistance. The activity/delivery enhancers decrease adverse effects, increase tissue and biofilm penetration, improve medication absorption, and enable tailored antibiotic administration. In order to lessen the antibiotic adverse effects and improve formulation stability and effectiveness against bacteria that are resistant to several drugs, this review offers insights into a variety of antibiotic activity enhancers, such as polymer, lipid, and silver-based systems.
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