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Abstract
To the Editor: Intravenous immunoglobulin (IVIG) is commonly used for the treatment of a wide range of autoimmune diseases1,2,3. The available data also suggest that IVIG has a steroid-sparing effect: either enhancing the steroid sensitivity or reducing the steroid dose4,5,6. These reports indicate that IVIG can be considered as a therapeutic choice in steroid-resistant autoimmune and inflammatory diseases such as dermatomyositis, asthma, and polymyositis. We aimed to identify the underlying molecular mechanisms by which IVIG therapy can restore steroid sensitivity and can as a “steroid-sparing” … Address correspondence to S.V. Kaveri; E-mail: srini.kaveri{at}crc.jussieu.fr
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