Abstract
The effect of somatostatin 1–14 (SS) on the natural killer (NK) activity of human peripheral blood lymphocytes was investigated. The NK activity was estimated by means of radioactive chromium ( 51Cr) assay with the use of human leukemia cells K 562 as targets. The previous exposure of lymphocytes obtained from healthy donors to somatostatin in the concentration of 10 −8 and 10 −6 M resulted in the enhancement of NK activity. The finding provides a further evidence of the immunomodulating somatostatin action.
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