Abstract
Hydrazine electrooxidation readily occurs on bare Au nanoparticles (AuNPs), whereas it does not on DNA-conjugated AuNPs. Thus, when DNA-conjugated AuNPs are used as electrocatalytic labels in electrochemical DNA detection, anodic current of hydrazine is not easily observed within the potential window because of the high overpotential caused by the slow electron-transfer kinetics on DNA-conjugated AuNPs as well as the slow electron tunneling between the AuNP and the indium−tin oxide (ITO) electrode. NaBH4 treatment significantly enhances the electrocatalytic activity of DNA-conjugated AuNPs. This enhancement substantially decreases the overpotential caused by the slow electron-transfer kinetics, and the anodic current of hydrazine can be measured within the potential window if the distance between the AuNP and the ITO electrode is not too large. The enhancement with NaBH4 treatment allows high signal current, and the low intrinsic electrocatalytic activity of ITO electrodes allows low background current. T...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
