Abstract
channels, providingprivileged cross-signaling between the DHP receptors (DHPRs)and RyRs (Sham et al., 1995; Adachi-Akahane et al., 1996). Inatrial myocytes lacking t-tubules, RyRs are also found in non-junctional or corbular SR throughout the central region of thecell without associated DHPRs (Sommer & Jennings, 1992;Carl et al., 1995; Hatem et al., 1997; Mackenzie et al., 2001).The mode of gating and the contribution of this set of RyRs toatrial functions remain uncertain. Confocal Ca
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