Abstract
AbstractNew cationic derivatives of starch are attractive targets for biomedical applications due to their propensity for electrostatically binding with anionic biomolecules, such as nucleic acids and certain proteins. In the first step, 1‐Butyl‐3‐methylimidazolium chloride [BMIM]Cl is used as a solvent to prepare tosyl starch from starch and tosyl chloride. The reaction between 1‐methylimidazole and tosyl starch produced cationic starch salt. Starch derivatives are characterized using elemental analysis, FT‐IR spectroscopy, 13C NMR, 1H NMR, and SEM analysis. The cationic starch derivative has an antimicrobial effect on all organisms tested and the minimal inhibitory concentration (MIC) recorded different values depending on what species is tested. The prepared cationic starch bearing substantial permanent positive charge exhibited high water solubility and can bind strongly with anionic surface, supporting their potential for a variety of applications such as antimicrobial surfaces. The cationic starch derivatives may be promising candidates for biomedical applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
