Abstract
The Omicron variant is quickly becoming the most common SARS-CoV-2 virus spreading throughout the world. To understand probable loss of protection against Omicron infection, it's critical to identify declines in viral neutralizing activity in serum of convalescent or vaccinated people. Antibodies against Omicron and various variants have been detected by scientists. These antibodies target non-evolving regions of the viral spike protein. A booster dose improves the quality and amount of the humoral immune response, which has been related to better protection against the disease's more severe signs. Vaccines and boosters must be provided promptly around the world to stop the virus from spreading.
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